I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as. Florencio Dra Soledad Giargei PintosĪll necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived. General San Jorge ManriqueĬomite de Etica Hospital Alta Complejidad El Cruce. The details of the IRB/oversight body that provided approval or exemption for the research described are given below:Ĭomite de Bioetica Hospital Interzonal General de Agudos Eva Peron de San Martin. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Laboratorio Pablo Cassara free provided the drug and placebo samples.Īcknowledgements: We thank the participating hospitals, their staff and persons included in this study. Ministerio de Ciencia, Tecnologia e Innovacion, Argentina. Publication and administrative costs were supported by: Programa de articulacion y fortalecimiento federal de las capacidades en ciencia y tecnologia COVID-19, Proyecto CABA 20. ![]() ![]() The study did not received support for hospitals, staff or patients involved. JMF and ML reports personal fees from Laboratorio Pablo Cassara, outside the submitted work. Implications of all the available evidence A simple intervention such as the administration of a nasal spray with Iota-Carrageenan, in addition to hand hygiene, use of personal protective equipment and social distancing, could provide additional protection until vaccines can be administered to the majority of the population. Iota-Carrageenan nasal spray appears to be a promising compound for safe and effective treatment of early symptoms of common cold.
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